Rejuran was first launched in South Korea and has since become one of the most well-documented and sought-after brands in regenerative aesthetics globally. What sets Rejuran apart from most competitors is not one single formulation, but a family of products – Healer, I and S – all built on the same polynucleotide technology (PN/PDRN) from salmon DNA. What differentiates them is not the active ingredient, but viscosity and concentration, adapted to different injection depths and treatment areas.
For clinics that want to offer best-in-class regenerative treatment, it is essential to understand that Healer, I and S are one family – not three unrelated products.
Rejuran is a brand originating in South Korea, developed by Pharma Research Bio, and based on polynucleotides (PN) and PDRN – long DNA chains extracted from salmon DNA. These molecules have high biocompatibility with human DNA and trigger the body’s own repair and regeneration mechanisms.
What has made Rejuran a true «word-of-mouth» phenomenon in the aesthetics community globally – and in the Nordics in particular – is the results: practitioners report noticeable improvement in skin quality, elasticity and moisture, and patients experience a natural rejuvenation without the «filled» effect that traditional fillers can give. The effect is biological, not mechanical.
PN (polynucleotides) are long chains of nucleotides that stimulate fibroblasts and promote collagen and elastin production. PDRN (polydeoxyribonucleotide) is a fraction of the same molecular family, with lower molecular weight and a documented anti-inflammatory effect. The entire Rejuran range – Healer, I and S – is built on this shared technology platform, adapted to different viscosities for different areas of use.
PN/PDRN from salmon DNA binds to adenosine A2A receptors on the fibroblasts and stimulates production of collagen type I and III, elastin and hyaluronic acid. At the same time, polynucleotides have documented anti-inflammatory properties and promote angiogenesis in the tissue. The result is a biological repair process that improves the skin structure itself from within – not a mechanical filling from the outside. This applies equally to Healer, I and S – only the viscosity is adapted to injection depth and purpose.
The most common misconception among new Rejuran users is that S is a completely different product from Healer and I. It is not. All three are built on the same PN/PDRN technology from salmon DNA – the difference lies in viscosity, concentration and pack size, adapted to different injection depths and treatment areas.
The original and most widely used variant. Universal skin booster for the face, neck, décolletage and hands.
Same PN technology as Healer, but lower viscosity – specially formulated for the thin, sensitive skin around the eyes.
Same PN technology as Healer, but in higher concentration and viscosity – gives more structural support for atrophic scars.
| Parameter | Healer | I | S |
| Technology | PN/PDRN, salmon DNA | PN/PDRN, salmon DNA | PN/PDRN, salmon DNA |
| Indication | General rejuvenation | Eye contour | Atrophic scars |
| Viscosity | Standard | Low | High |
| Pack size | 2 × 2 ml | 1 × 1 ml | 1 × 1 ml |
| Technique | Nappage 15–30° | Micropapules | Punctate, mid–deep dermis |
| Duration | 6–12 months | 6–12 months | Progressive build-up |
| Classification | Medical device | Medical device | Medical device |
Regenerative aesthetics is the fastest-growing segment in the Nordic aesthetics industry. Patients increasingly seek treatments that give natural, long-lasting results – not mechanical volume. Rejuran positions clinics clearly in this segment.
Injectable products are not an area for compromise. Cold chains, storage requirements, traceability and regulatory documentation are not details – they are fundamental prerequisites for clinical safety and patient safety. And this is where the choice of distributor means everything.
BC Nordic is an authorised distributor of the Rejuran range in the Nordics. As a specialised B2B supplier of medical aesthetics products we take care of every step of the distribution – from import and storage to delivery to the clinic.
Contact BC Nordic – we lead the way in regenerative aesthetic medicine
Injectable aesthetics products bought through unauthorised channels – online shops without a Nordic or European presence, parallel imports or uncertified intermediaries – give no guarantee of cold chain, authenticity, shelf life or regulatory status. The Rejuran range has strict requirements for documentation and traceability as a medical device. Always choose an authorised distributor.
Yes. Many clinics offer a combination protocol in which Rejuran Healer is used for the face, neck and décolletage, and Rejuran I for the eye contour treatment – in one and the same session. The two products are formulated with different viscosities adapted to different skin thicknesses, and complement each other optimally.
Rejuran Healer and Rejuran® S are built on the same PN technology – the difference lies in viscosity and concentration, not in the active ingredient. Healer is distributed broadly in the dermis for general skin rejuvenation. Rejuran® S has higher viscosity and is injected punctately in the mid to deep dermis for atrophic scars.
Rejuran® S is intended for patients with atrophic scars, particularly acne scars, and structural skin defects. Like the other products in the Rejuran range it is classified as a medical device and requires the practitioner to have documented competence in dermal injection. Contact BC Nordic for product-specific information and training resources.
Both products give results that typically last 6–12 months, depending on skin condition, age, lifestyle and protocol. Consistent maintenance treatments prolong the effect.
Rejuran Healer, Rejuran I and Rejuran® S are available to clinics and authorised practitioners through BC Nordic. Get in touch or visit our online shop at bcnordics.com.
BC Nordic is an authorised distributor of the entire Rejuran range in the Nordics – Healer for general facial rejuvenation, I for eye contour treatment and S for regenerative scar treatment. Traceable chain, correct storage and full regulatory documentation.
See the Rejuran range →