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45 mg of high molecular weight hyaluronic acid (H-HA) is combined with 45 mg of low molecular weight HA (L-HA)
This blend is then heated using NAHYCO technology, breaking the hydrogen bonds that connect the H-HA molecules. The temperature of the mixture is then lowered, "causing hydrogen bonds to form between the H-HA and L-HA molecules". This creates and stabilises "hybrid cooperative complexes". The result is a new molecule - Profhilo® Structura.